Biomedical technology

Laura Mignanelli, M. Sc.

 

Analysis of the vibrations generated by the human body

State of the art/Motivation

  • The heartbeat originates characteristic vibrations on the thorax which can be measured with a Laser-Doppler-Vibrometer (LDV)
  • The detection of the heartrate, heartrate variability and the pulse wave velocity etc. were already demonstrated
  • The detection of the PR time is also possible

Aim of the work

  • Comprehensive understanding of how and with what uncertainty vibration measurements on the human body can be used for medical diagnosis

Methods

  • Application of a single point vibrometer and a robot supported scanning-vibrometer
  • Comparison of the vibration signals with electrocardiographic signals
  • Development of algorithms for parameter recognition
  • Analysis of the influence of the measuring condition for the determination of the characteristic parameters
  • Multichannel-Vibrometer to study the vibration in several points
  • Analysis of 3D vibration direction with multichannel vibrometer

Results

  • In addition to the heartbeat, the detection of the contraction of the atria can be identified
  • Detection of AV-blocks with the Laser Doppler vibrometry is possible
  • Recommended settings for filters and set up are obtained
  • The velocity vector of skin movement changes direction during a complete heartbeat: no uniform measurement direction
  • Determination of the uncertainty contribution of the laser beam orientation for laser Doppler vibrometer measurements on the carotid artery

Outlook

  • Use the vibrations generated in the human body for medical diagnosis
  • Determination of the uncertainty contribution of laser beam orientation for laser Doppler vibrometer measurements on the chest
  • Investigation of the dependence of vibration on anatomical and physiological features

Publications

  • L. Mignanelli and C. Rembe:
    Uncertainty contribution of the laser-beam orientation for laser Doppler vibrometer measurements at the carotid artery.

    In: Journal of Physics: Conference Series, Vol. 1149, Conference 1, 2018.
    DOI: 
    10.1088/1742-6596/1149/1/012025.
  • L. Mignanelli, G. Bauer, M. Klarmann, H. Wang and C. Rembe:
    Influence of the measuring condition on vibrocardiographic signals acquired on the thorax with a laser Doppler vibrometer. 
    In: Proceedings of the European Conferences on Biomedical Optics (ECBO), Munich, Germany, June 2017, p. 1041105. 
    DOI: 10.1117/12.2282894.
  • L. Mignanelli, A. Luik, K. Kroschel, L. Scalise and C. Rembe: 
    Auswertung von Vibrometersignalen zur Bestimmung kardiovaskulärer Parameter. 
    In: tm - Technisches Messen. Vol. 83, pp. 462-473, Sept. 2016. 
    DOI: 10.1515/teme-2015-0113.
  • L. Mignanelli and C. Rembe: 
    Algorithm for Automatic Detection of the Cardiovascular Parameter PR-Interval from LDV-Velocity Signals. 
    In: Proceedings of the 12th Int. Conference on Vibration Measurements by Laser and Noncontact Techniques, Ancona, Italy, June/July 2016. 
    DOI: 10.1063/1.4952666.
  • A. Luik, L. Mignanelli, K. Kroschel, C. Schmitt, C. Rembe and L. Scalise: 
    Laser Doppler Vibrometry for Non-Contact Identification and Classification of AV-Blocks. 
    Future Cardiology. Vol. 12, pp. 269-279, May 2016. 
    DOI: 10.1063/1.4879597.
  • L. Mignanelli, A. Luik, K. Kroschel, L. Scalise and C. Rembe
    Laser Doppler Vibrometer in der Medizin
    in Proceedings of the XXIX. Messtechnisches Symposium des AHMT, Ilmenau, Germany, Sept. 2015, pp. 107-114.
Investigation of the vibrations in several points (left) and of the influence of the laser beam orientation on the vibration pattern (right) with multipoint vibrometer
 

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